Journal of Bionic Engineering ›› 2022, Vol. 19 ›› Issue (3): 737-751.doi: 10.1007/s42235-022-00152-w
Current Status and Outlook of Porous Zn-based Scaffolds for Bone Applications: A Review
Abdul Hakim Md Yusop1, Mokhamad Fakhrul Ulum2, Ahmed Al Sakkaf3, Hadi Nur1,4
- 1 Center for Sustainable Nanomaterials, Ibnu Sina Institute for Scientifc and Industrial Research, Universiti Teknologi Malaysia, 81310 Johor Bharu, Malaysia 2 Faculty of Veterinary Medicine, Bogor Agricultural University, Bogor 16680, Indonesia 3 School of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 Johor Bharu, Malaysia 4 Center of Advanced Materials for Renewable Energy (CAMRY), Universitas Negeri Malang, Malang 65145, Indonesia
Current Status and Outlook of Porous Zn-based Scaffolds for Bone Applications: A Review
Abdul Hakim Md Yusop1, Mokhamad Fakhrul Ulum2, Ahmed Al Sakkaf3, Hadi Nur1,4
- 1 Center for Sustainable Nanomaterials, Ibnu Sina Institute for Scientifc and Industrial Research, Universiti Teknologi Malaysia, 81310 Johor Bharu, Malaysia 2 Faculty of Veterinary Medicine, Bogor Agricultural University, Bogor 16680, Indonesia 3 School of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 Johor Bharu, Malaysia 4 Center of Advanced Materials for Renewable Energy (CAMRY), Universitas Negeri Malang, Malang 65145, Indonesia
摘要： Over the past 5 years, many works have been performed to reveal the potentials of Zinc (Zn)-based materials as temporary bone scaffolds with the expectation that their emergence could address some of the main concerns associated with magnesium- and iron-based materials. Thanks to the emerging Additive Manufacturing (AM) technology, it facilitates the optimization of the design and production of topological porous Zn-based materials suited for bone scaffolds. Since the studies on the porous Zn-based scaffolds are on the rise, we provide the most current progress in the development of porous Zn-based scaffolds for bone applications. The impacts of recently developed topological design from the AM as well as the advanced dynamic-flow corrosion on their corrosion, mechanical properties, and in vitro biocompatibility are also presented. Plus, we identify a number of research gaps and the challenges encountered in adopting porous Zn-based scaffolds for orthopedic applications and suggest some promising areas for future research.