Journal of Bionic Engineering ›› 2021, Vol. 18 ›› Issue (3): 584-599.doi: 10.1007/s42235-021-0039-6

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Potential Application of Entangled Porous Titanium Alloy Metal Rubber in Artificial Lumbar Disc Prostheses

Zhiying Ren1,2*, Jingfei Huang1,2, Hongbai Bai1,2, Rui Jin1,2, Fangqi Xu1,2, Jie Xu3*   

  1. 1. College of Mechanical Engineering and Automation, Fuzhou University, Fuzhou 350116, China
    2. Metal Rubber Engineering Research Center, Fuzhou University, Fuzhou 350116, China
    3. Department of Orthopedics, Fujian Provincial Hospital, Fuzhou 350001, China
  • 收稿日期:2020-09-30 修回日期:2021-01-29 接受日期:2021-03-10 出版日期:2021-05-10 发布日期:2021-11-30
  • 通讯作者: Zhiying Ren, Jie Xu E-mail:renzy@fzu.edu.cn, jiexud@126.com
  • 作者简介:Zhiying Ren1,2*, Jingfei Huang1,2, Hongbai Bai1,2, Rui Jin1,2, Fangqi Xu1,2, Jie Xu3*

Potential Application of Entangled Porous Titanium Alloy Metal Rubber in Artificial Lumbar Disc Prostheses

Zhiying Ren1,2*, Jingfei Huang1,2, Hongbai Bai1,2, Rui Jin1,2, Fangqi Xu1,2, Jie Xu3*   

  1. 1. College of Mechanical Engineering and Automation, Fuzhou University, Fuzhou 350116, China
    2. Metal Rubber Engineering Research Center, Fuzhou University, Fuzhou 350116, China
    3. Department of Orthopedics, Fujian Provincial Hospital, Fuzhou 350001, China
  • Received:2020-09-30 Revised:2021-01-29 Accepted:2021-03-10 Online:2021-05-10 Published:2021-11-30
  • Contact: Zhiying Ren, Jie Xu E-mail:renzy@fzu.edu.cn, jiexud@126.com
  • About author:Zhiying Ren1,2*, Jingfei Huang1,2, Hongbai Bai1,2, Rui Jin1,2, Fangqi Xu1,2, Jie Xu3*

摘要: Entangled Porous Titanium Alloy Metal Rubber (EPTA-MR) was used as a nucleus pulposus material in the design of non-fusion intervertebral disc prosthesis for the first time. A novel artificial lumbar intervertebral disc prosthesis was designed by reconstructing the lumbar model with reverse engineering technology, and the biomechanical behavior of the prosthesis was simulated under varied working conditions. The nucleus pulposus size was determined by the actual size of human prosthesis. EPTA-MR samples with different densities were prepared by medical titanium alloy wire experimental studies were conducted on static stiffness, damping energy consumption, and fatigue life. The results indicated that the static stiffness of EPTA-MR could reach approximately 1500 N·mm?1, and its loss factor remained higher than 0.2, and the variation range was relatively small, with excellent vibration damping capacity and bearing capacity. Among them, the overall performance of EPTA-MR with a density of 2.5 g·cm?3 was closer to that of the physiologic intervertebral disc. A macro experiment of five million fatigue vibration tests combined with microstructure observation exhibited a wear rate of only 0.9396 g·MC?1, with no noticeable change in the internal micro-morphology. Therefore, the EPTA-MR has a broad application prospect as the nucleus pulposus material of artificial intervertebral disc prosthesis.


关键词: artificial intervertebral disc prosthesis, biomechanical properties, entangled porous titanium alloy metal rubber (EPTA-MR), fatigue life, vibration damping

Abstract: Entangled Porous Titanium Alloy Metal Rubber (EPTA-MR) was used as a nucleus pulposus material in the design of non-fusion intervertebral disc prosthesis for the first time. A novel artificial lumbar intervertebral disc prosthesis was designed by reconstructing the lumbar model with reverse engineering technology, and the biomechanical behavior of the prosthesis was simulated under varied working conditions. The nucleus pulposus size was determined by the actual size of human prosthesis. EPTA-MR samples with different densities were prepared by medical titanium alloy wire experimental studies were conducted on static stiffness, damping energy consumption, and fatigue life. The results indicated that the static stiffness of EPTA-MR could reach approximately 1500 N·mm?1, and its loss factor remained higher than 0.2, and the variation range was relatively small, with excellent vibration damping capacity and bearing capacity. Among them, the overall performance of EPTA-MR with a density of 2.5 g·cm?3 was closer to that of the physiologic intervertebral disc. A macro experiment of five million fatigue vibration tests combined with microstructure observation exhibited a wear rate of only 0.9396 g·MC?1, with no noticeable change in the internal micro-morphology. Therefore, the EPTA-MR has a broad application prospect as the nucleus pulposus material of artificial intervertebral disc prosthesis.


Key words: artificial intervertebral disc prosthesis, biomechanical properties, entangled porous titanium alloy metal rubber (EPTA-MR), fatigue life, vibration damping