J4 ›› 2013, Vol. 10 ›› Issue (3): 350-358.doi: 10.1016/S1672-6529(13)60230-9

• 论文 • 上一篇    下一篇

  

  • 收稿日期:2011-11-10 修回日期:2013-06-10 出版日期:2013-07-10 发布日期:2013-07-10

A Femur-Implant Model for the Prediction of Bone Remodeling Behavior Induced by Cementless Stem

He Gong, Lingyan Kong, Rui Zhang, Juan Fang, Meisheng Zhao   

  1. 1. State Key Laboratory of Automotive Simulation and Control, Jilin University, Changchun 130025, P. R. China
    2. Department of Engineering Mechanics, Jilin University, Changchun 130025, P. R. China
    3. Department of Cataract, Eye Hospital of the Second Clinical Hospital of Jilin University, Jilin University,
    Changchun 130051, P. R. China
  • Received:2011-11-10 Revised:2013-06-10 Online:2013-07-10 Published:2013-07-10
  • Contact: Meisheng Zhao E-mail:zhaoms1961@sina.com

关键词: functionally graded material, bone remodeling, stress shielding, proximal femur, implant

Abstract:

Bone remodeling simulation is an effective tool for the prediction of long-term effect of implant on the bone tissue, as well as the selection of an appropriate implant in terms of architecture and material. In this paper, a finite element model of proximal femur was developed to simulate the structures of internal trabecular and cortical bones by incorporating quantitative bone functional adaptation theory with finite element analysis. Cementless stems made of titanium, two types of Functionally Graded Material (FGM) and flexible ‘iso-elastic’ material as comparison were implanted in the structure of proximal femur respectively to simulate the bone remodeling behaviors of host bone. The distributions of bone density, von Mises stress, and interface shear stress were obtained. All the prosthetic stems had effects on the bone remodeling behaviors of proximal femur, but the degrees of stress shielding were different. The amount of bone loss caused by titanium implant was in agreement with the clinical obser-vation. The FGM stems caused less bone loss than that of the titanium stem, in which FGM I stem (titanium richer at the top to more HAP/Col towards the bottom) could relieve stress shielding effectively, and the interface shear stresses were more evenly distributed in the model with FGM I stem in comparison with those in the models with FGM II (titanium and bioglass) and titanium stems. The numerical simulations in the present study provided theoretical basis for FGM as an appropriate material of femoral implant from a biomechanical point of view. The next steps are to fabricate FGM stem and to conduct animal experi-ments to investigate the effects of FGM stem on the remodeling behaviors using animal model.

Key words: functionally graded material, bone remodeling, stress shielding, proximal femur, implant