Abstract: In bone tissue engineering, scaffold design must achieve specific mechanical compatibility with implantation sites, critically determining implant performance. This study developed four cylindrical Ti6Al4V bone scaffolds via selective laser melting (SLM), incorporating distinct lattice architectures: Face-Centered Cubic (FCC), Body-Centered Cubic (BCC), Glass Sponge (GS), and Auxetic Structures (AS). Integrated experimental characterization and finite element simulations revealed exceptional mechanical superiority of FCC scaffolds, demonstrating 7-fold greater maximum stress compared to BCC, GS, and AS counterparts. Furthermore, FCC scaffolds exhibited optimal performance metrics including plateau stress (1.2–1.4 GPa), densification strain (0.15–0.25), energy absorption (85–100 MJ/m3), and specific energy absorption (45–55 kJ/kg). These findings confirm that the unique energy dissipation mechanisms inherent to FCC lattice geometry significantly enhance energy absorption efficiency. The study provides a theoretical foundation for developing mechanically adaptive bone implants, particularly advancing clinical applications requiring enhanced energy absorption capabilities.

Key words: Bone scaffold')">Bone scaffold, SLM, Lattice structure, Ti6Al4V, Energy absorption