Abstract: Over the last decade, computational methods have been intensively applied to a variety of scientific researches and engi-neering designs. Although the computational fluid dynamics (CFD) method has played a dominant role in studying and simu-lating transport phenomena involving fluid flow and heat and mass transfers, in recent years, other numerical methods for the simulations at meso- and micro-scales have also been actively applied to solve the physics of complex flow and fluid-interface interactions. This paper presents a review of recent advances in multi-scale computational simulation of biomimetics related fluid flow problems. The state-of-the-art numerical techniques, such as lattice Boltzmann method (LBM), molecular dynamics (MD), and conventional CFD, applied to different problems such as fish flow, electro-osmosis effect of earthworm motion, and self-cleaning hydrophobic surface, and the numerical approaches are introduced. The new challenging of modelling biomi-metics problems in developing the physical conditions of self-clean hydrophobic surfaces is discussed.

Key words: computational simulation, biomimetics, macro-, meso-, micro-scale, hydrophobic, surfaces