J4 ›› 2013, Vol. 10 ›› Issue (2): 156-161.doi: 10.1016/S1672-6529(13)60210-3

• 论文 • 上一篇    下一篇

Xing Xiao, Haiying Yu, Qingsan Zhu, Guangyu Li, Yang Qu, Rui Gu   

  • 收稿日期:2012-12-12 修回日期:2013-02-12 出版日期:2013-04-06 发布日期:2013-04-10
  • 作者简介:Xing Xiao, Haiying Yu, Qingsan Zhu, Guangyu Li, Yang Qu, Rui Gu

In Vivo Corrosion Resistance of Ca-P Coating on AZ60 Magnesium Alloy

Xing Xiao, Haiying Yu, Qingsan Zhu, Guangyu Li, Yang Qu, Rui Gu   

  1. 1. First Hospital of Jilin University, Changchun 130021, P. R. China
    2. Shandong Qianfoshan Hospital, Jinan 250014, P. R. China
    3. Shandong Tumour Hospital, Jinan 250117, P. R. China
    4. College of Materials Science and Engineering, Jilin University, Changchun 130022, P. R. China
    5. China Japan Union Hospital of Jilin University, Changchun 130033, P. R. China
  • Received:2012-12-12 Revised:2013-02-12 Online:2013-04-06 Published:2013-04-10
  • Contact: Rui Gu E-mail:ccguruij@hotmail.com
  • About author:Xing Xiao, Haiying Yu, Qingsan Zhu, Guangyu Li, Yang Qu, Rui Gu

Abstract:

Magnesium-based alloys are frequently reported as potential biodegradable orthopedic implant materials. Controlling the degradation rate and mechanical integrity of magnesium alloys in the physiological environment is the key to their applications. In this study, calcium phosphate (Ca-P) coating was prepared on AZ60 magnesium alloy using phosphating technology. AZ60 samples were immersed in a phosphating solution at 37 ± 2 ?C for 30 min, and the solution pH was adjusted to 2.6 to 2.8 by adding NaOH solution. Then, the samples were dried in an attemperator at 60 ?C. The degradation behavior was studied in vivo using Ca-P coated and uncoated magnesium alloys. Samples of these two different materials were implanted into rabbit femora, and the corrosion resistances were evaluated after 1, 2, and 3 months. The Ca-P coated samples corroded slower than the un-coated samples with prolonged time. Significant differences (p < 0.05) in mass losses and corrosion rates between uncoated samples and Ca-P coated samples were observed by micro-computed tomography. The results indicate that the Ca-P coating could slow down the degradation of magnesium alloy in vivo.

Key words: Ca-P coating, mass loss, micro-computed tomography, corrosion resistance, magnesium alloy